Search on: DUAL SPECIFICITY PHOSPHATASE 2 
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Descriptor English:   Dual Specificity Phosphatase 2 
Descriptor Spanish:   fosfatasa 2 de doble especificidad 
Descriptor Portuguese:   Fosfatase 2 de Especificidade Dupla 
Synonyms English:   PAC 1 Phosphatase
PAC-1 Phosphatase
PAC1 Phosphatase
Phosphatase, PAC-1
Phosphatase, PAC1  
Tree Number:   D08.811.277.352.650.587.250
D08.811.277.352.650.625.225.250
D08.811.277.352.650.775.250.250
D08.811.641.755.250
D12.644.360.268.250
D12.644.360.445.250
D12.776.476.268.250
D12.776.476.445.250
Definition English:   A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for EXTRACELLULAR SIGNAL-REGULATED MAP KINASES and is primarily localized to the CELL NUCLEUS. 
History Note English:   2008(1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52689 
Unique Identifier:   D054641 

Occurrence in VHL:
 

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